The best way to help the body stimulate/metabolism and activate the fat burning abilities is to eat thermogenic foods, drink plenty of water, exercise regularly (Paul 2009).
Fat cells in the body release a hormone that signals to the brain that there is enough energy stored. This triggers your body to burn energy stored as fat.
Depending on body shape, men generally tend to lose fat first from their trunk, followed by their arms and then their legs. This means that although men tend to store abdominal fat, it is also one of the first place they lose it.
Deoxycholic acid is a US FDA approved fat dissolving material and a naturally occurring human bile acid, which is a metabolic by-product of human intestinal bacteria. In the human body, deoxycholic acid is used in the emulsification of fats for absorption in the intestine.
The hormones leptin and insulin, sex hormones and growth hormone influence our appetite, metabolism (the rate at which our body burns kilojoules for energy), and body fat distribution. People who are obese have levels of these hormones that encourage abnormal metabolism and the accumulation of body fat.
Meet Leptin — A Hormone That Regulates Body Weight
Leptin's primary target is in the brain — particularly an area called the hypothalamus. Leptin is supposed to tell your brain that — when you have enough fat stored — you don't need to eat and can burn calories at a normal rate (4).
B-complex vitamins: These help metabolize carbohydrates, fats, and proteins, activating stored energy instead of letting it turn to fat. Niacin, vitamin B-6, and iron: This impressive trio increases your body's production of the amino acid L-carnitine to help burn fat.
Apples, Soy foods and Whole Grains are natural food sources that effectively block fat absorption. These food sources don't just block fat absorption but also give energy to the body in a healthier manner.
Eat Your Carbs During the Day
Consume the bulk of your calories, particularly carbohydrates, during daytime hours and less in the early evening. You'll go to bed with less of the hormone insulin in your blood, so your body can metabolize fat for energy while you sleep.
As fat digestion requires numerous enzymes, various conditions can affect this process and, as a result, absorption. Liver disorders, small bowel syndrome, and problems with the small intestine can make it more difficult for the body to digest and absorb fat.
Calcium: It helps you burn more fat stored in the body. Prevents your body from storing fat.
Lemon water can promote fullness, support hydration, boost metabolism and increase weight loss. However, lemon water is no better than regular water when it comes to losing fat. That being said, it is tasty, easy to make and can be used as a low-calorie replacement for higher-calorie beverages.
Chang said that copper could potentially play a role in restoring a natural way to burn fat. The nutrient is plentiful in foods such as oysters and other shellfish, leafy greens, mushrooms, seeds, nuts and beans.
Answer From Brent A. Bauer, M.D. There's no solid evidence that vitamin B-12 injections aid weight loss. Vitamin B-12 is a water-soluble B complex vitamin found naturally in a variety of foods, including meat, fish and dairy products.
 It was established that zinc deficiency significantly inhibited leptin secretion from the fatty tissue and IL-2 and TNF-α levels decreased parallel to inhibited leptin levels.
Leptin is a hormone produced naturally in the body that helps regulate feelings of satiety (fullness or hunger). Because of this, marketers commonly promote leptin supplements as a weight-loss aid. But these supplements don't actually contain leptin, which means they're unlikely to lead to weight loss.
Leptin isn't a vitamin or mineral. You can't absorb it from a pill. In fact, “leptin supplements” don't contain any actual leptin. If they did, your stomach would simply digest them before they could have any effect on your body.